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Penny Proud (voiced by Kyla Pratt) is the main protagonist and the 14-year-old African-American girl who is usually embarrassed by the way her father, Oscar, acts. She enjoys hanging out with her friends, even though they have gotten her into trouble, and left her to face danger by herself many times. She sometimes listens to and always respects her parents, but often caves in to peer pressure. She is also a feminist at times, and is very logical. She is a very talented singer as shown when she becomes a solo singer for Wizard Kelly productions, but quits after missing her old life. Penny's a Straight A student. She's on the Football team and the Newspaper Staff. Penny tried out for cheerleading, but due to having an accident with the stage being converted into a giant CD, LaCienega got the last spot on the cheerleading squad. Penny is also good at reciting poetry and becomes jealous when Dijonay becomes just as good as her. In The Proud Family Movie, Penny turns 16, and she begins to want independence, but her father has issues letting her go. She saves the world and makes up with him, and he finally realizes she's her own person who can make her own decisions.
Oscar Proud (voiced by Tommy Davidson) is the overprotective father of Penny, BeBe and CeCe, husband of Trudy, younger brother of Bobby and son of Suga Mama, who is characterized as obnoxious and immature, but still a well-meaning, friendly man whose ambitions and failed attempts at fame and fortune often cloud his judgement. Oscar is an amateur entrepreneur despite his job as a telemarketer for the fictional Kelly Inc. He is very hyper, immature, childish, and semi-dimwitted, though considered intelligent in persona in an almost Homer Simpson manner. Oscar owns a business and produces a venomous brand of snack food called "Proud Snacks." Oscar's biggest weaknesses are money and attractive women
Trudy Proud (née Parker) (voiced by Paula Jai Parker) is the veterinarian mother of Penny, BeBe and CeCe, wife of Oscar, daughter-in-law of Suga Mama and sister-in-law of Bobby. She comes from a relatively wealthy family which includes her sister Diana, who is a famous actress. She often gives Penny advice when Penny is in trouble while at the same time, she frequently forces Oscar to see the logical side of an argument and to allow Penny to have a voice. Trudy is the second most sensible member of the family along with Penny, though she can be bossy sometimes. he comes from somewhat of a wealthy family, her father also being a doctor.
Suga Mama Proud (voiced by Jo Marie Payton) is Penny, BeBe, and CeCe's hip, wrestling-loving paternal grandmother, Oscar and Bobby's mother and Trudy's mother-in-law who does Tae Bo. She is nice but sassy, and always gets straight to the point when she talks. She can even tease and beat up Oscar, but loves him deep down. Her age is unknown (although in one episode it said she had a driver's license that expired in 1938), and often made fun of by her son. An event from twenty years ago shows her looking exactly the same as before. Suga Mama is in love with Papi. On the contrary Papi despises Suga Mama and often makes rude remarks about her in Spanish which she thinks are compliments, she shows extra amounts of love for her poodle, Puff.
BeBe & CeCe Proud (both voiced by Tara Strong) are Penny's trouble-making 1-year-old baby twin siblings. BeBe is a boy with an afro and always has a bottle in his mouth, while CeCe is a girl with brown hair and a pink dress with pigtails. BeBe and CeCe are namesakes of the gospel music brother and sister duo, BeBe & CeCe Winans. CeCe is the older twin. They love Penny very much, but at points play too roughly with her. They are often seen playing with Puff, and most of the time, Puff ends up getting injured. Their voices are similar to Dil Pickles on Rugrats, whose voice is by the same actress.
Puff the Dog (voiced by Tara Strong in the first season, Carlos Alazraqui in the second season and the movie) is Suga Mama's beloved pet poodle. Puff is often tormented by the baby twins, BeBe & CeCe, who play roughly with him. He does, however, show a soft side for Penny.
LaCienega Boulevardez (voiced by Alisa Reyes) is Penny's Hispanic-American frenemy and the daughter of Felix and Sunset Boulevardez. She is the most popular and beautiful girl in Penny's school, caring a great deal about her popularity and image and displaying a rather nasty bullying attitude; Penny in particular rarely gets along with her. LaCienega and her mother Sunset are named after La Cienega Boulevard and Sunset Boulevard, two Los Angeles area arterial roads that meet in West Hollywood, California.
Dijonay Jones (voiced by Karen Malina White) is Penny's selfish and untrustworthy yet enthusiastic and caring best friend. She has an obsessive crush on Sticky. She also loves to gossip and has gotten Penny in trouble many times. Dijonay's name is a pun on the name of Best Foods'/Hellmann's Dijonnaise, and she has nine younger siblings, all named after spices, seasonings and condiments.
Zoey Howzer (voiced by Soleil Moon Frye) is timid, shy, and very insecure about her looks and wants to be accepted. Zoey is known for being a follower and Penny often has to talk sense into her. Her family is Jewish.
Sticky Webb (voiced by Orlando Brown) is Penny's other best friend. He is shown as a cool tech nerd who is able to build or hack any type of device, and after Zoey, he is Penny's most loyal friend.
