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Amber Montana as Taylor Hathaway, the first daughter of Michelle Hathaway, and the older sister of Frankie Hathaway. As seen in the first episode, she is a talented gymnast who cares about her work and is easily agitated by her family and the Prestons.
Curtis Harris as Miles Preston, the older son of Ray and older brother of Louie. He is the most well-mannered of the Preston ghosts, and tries the hardest to socialize with humans, especially Taylor. Miles does his best to help Taylor with her problems, but he tends to do more harm than good.
Benjamin Flores Jr. as Louis "Louie" Preston, the son of Ray Preston, and is Miles Preston's younger brother. He tends to be rude and a little bit on the sarcastic side. He loves haunting and scaring people, though he hasn't quite mastered it yet. Louie doesn't understand why the Hathaways have to live with them in their house and isn't always so nice to the Hathaways, but he gradually accepts them and becomes best friends with Frankie.
Breanna Yde as Francesca "Frankie" Hathaway, the second daughter of Michelle Hathaway, and the younger sister of Taylor Hathaway. She is considered strange by her peers, and embraces the idea of living with ghosts. Frankie doesn't easily get along with her older sister, Taylor, because they have different ways of dealing with things. Frankie and Louie have a complicated relationship because Frankie is often better at scaring people than he is, but they are still best friends. In the episode "Haunted Doll" it was revealed that her full name is Francesca.
Ginifer King as Michelle Hathaway, the good-hearted single mother of Taylor and Frankie. She is divorced and along with her two daughters lives with the Prestons. Michelle is a skilled baker who owns a bakery called Pie Squared. Michelle tries to get along with her daughter, Taylor, but they always think of things differently and their problems tend to be controversial. Michelle and Ray also find a complicated relationship because of their different styles of parenting.
Chico Benymon as Raymond "Ray" Preston, the father of Miles and Louie. As seen in the first episode, he plays the saxophone. Ray prefers a laid-back lifestyle, so he isn't very good at disciplining his sons when they misbehave.