Siri is a surname of Italian origin. Notable people with the surname include:
Alejandro Siri (born 1963), Argentine field hockey player
Florent Emilio Siri (born 1965), French film director
Giuseppe Siri (1906–1989), Italian cardinal
José Siri (born 1995), a Dominican professional baseball outfielder
Martin Siri (born 1979), Argentine cricketer
Nicolás Siri (born 2004), Uruguayan footballer
Preecha Siri, Karen-Thai conservationist and environmentalist
Román Fresnedo Siri (1903–1975), Uruguayan architect
Santipap Siri (born 1985), Thai footballer
Vittorio Siri (1608–1685), also known as Francesco Siri, Italian mathematician and Benedectine monk
William Siri (1919–2004), American biophysicist
