Plot
While investigating rumors of a mystical "healing earth" whose powers are said to flow forth from the sacred Gudjara Mountain, geologists Philip and Betsy Ames are killed in a cave-in, leaving their young daughter, Janet, an orphan. Janet is adopted by Shaman, a woman of the native Zambouli tribe, and because of a prophecy about the cave-in ("when the sacred mountain cries out"), she is viewed as a child of the gods and renamed Sheena, "Queen of the Jungle".
As Sheena grows up, she learns much from Shaman about the lore of the jungle and the ways of all its creatures. She is even entrusted with the secret of telepathic communication with the animals. Outsiders rarely disturb their territory, since that part of Tigora is under the special protection of King Jabalani.
Trouble is brewing in Tigora. King Jabalani's ex-football champion younger brother, Prince Otwani is conspiring with his brother's fiancée, Countess Zanda to have Jabalani assassinated so they can exploit the titanium-rich Zambouli land. Experiencing a vision foretelling Jabalani's death, Shaman hastens to Tigora's capital of Azan to try to warn him, but is arrested by corrupt police officers working for Zanda.
Otwani's old friend, reporter Vic Casey and his cameraman, Fletch Agronsky are in Tigora to do a story on Otwani. When Jabalani is killed and Shaman is framed for it, Vic and Fletch realize that they are on to a much bigger story than they had anticipated. Heading to a remote prison compound to interview Shaman, they bear witness to her rescue by Sheena and her animal friends; Chango the elephant, Marika the zebra and Tiki the chimpanzee. As they escape back into the jungle after destroying the prison, Vic and Fletch follow. However, Shaman soon dies from her injuries.
Otwani obtains the services of Colonel Jorgensen and his small army of soldier mercenaries, the Black Berets. Their mission is to eradicate the Zambouli people so their territory will be open for strip-mining. Vic join forces with Sheena to stop the evil prince and his army, along the way, Vic and Sheena fall in love.
The climax takes place on the African Serengeti. Zanda captures Sheena on a helicopter and attempts to shove her down the Zambuli Falls, but Sheena connects telepathically to a flock of flamingos that attack the helicopter and throw Zanda down the waterfalls to her death. Sheena leads her people against the mercenaries and Otwani. Sheena successfully shoots Otwani in the heart with her arrow and fulfills the prophecy, but she is also positioned to be hit by Otwani's vehicle. Vic saves her life by crashing into Otwani's vehicle; resulting in severe burn wounds. Vic is healed with the earth and wants to stay with Sheena, but realizes that if he tells his story to the outside world, then other corporations will destroy Sheena's home.
Vic and Sheena have sex before parting ways. Later, he and Fletch leave on an airplane back to New York. Before leaving, Sheena records a farewell message on his tape recorder wishing him a safe journey. At the end the film, Sheena takes a ride on Marika through the Serengeti.