Solo work
In 2009, after thirteen years of artistic activity with her sister, she debuted as a solo artist with the single "Alone", an English-language song with black, soul and R&B atmospheres. The physical EP remains at the top of the single PMI/nielsen ranking of independent labels for 7 weeks in a row. The project combines the musical part with the visual part with a video (candidate for the Italian Videoclip Award 2009 and candidate for the Italian Independent Videoclip Award) shot by the fashion photographer Paolo Santambrogio.
In 2012, Iezzi participated in another musical project with the song "In adorazione di te", a duet with an alternative artist and producer Stiv where, in addition to participating as a singer in the song, she co-produces and studies the creative idea for the video that accompanies the piece of music that sees her as co-starring. A few months later, she published the EP Xcept You. The song, from the disco-dance atmospheres of the late 70s, is distributed only digitally. In the same year she began performing as a DJ, music selector and interpreter, both for evenings in clubs and discos, and for special events. In March 2014, she participated as a coach of the dance group Bad Boys on the Rai 1 talent show La pista, hosted by Flavio Insinna. The following June, she starred in a short cameo in the television film Ti amo troppo per dirtelo, directed by director Marco Ponti.
On 24 June 2016, her single "Lovenight" was released. In the following November, she starred in Fabio Volo's TV series Untraditional, broadcast for nine episodes on channel 9 in the irreverent role of Volo's ex-girlfriend. On 5 December 2017, she released the Christmas album A Merry Little Christmas, the first album of her career. On 29 November 2019, she released another edition of the album, A Merry Little Christmas (Deluxe Edition), with three other new songs.
On 10 January 2020, she released the single "LTM" with the collaboration of Myss Keta. On 6 July, she released the single "Mon Amour". In the fall of the same year, she was a music expert in the TV8 program Vite da copertina.
On 8 December 2022, she was a guest judge of the final of the second edition of Drag Race Italia. On 30 December 2022, she sang with Benjamin Ingrosso and the Royal Stockholm Philharmonic Orchestra. They performed Un giorno crescerai, with the text written by Iezzi. In October 2023, she became a judge on the third season of Drag Race Italia. On 13 November 2023, she released the single "The Queens", the soundtrack of Drag Race Italia.
Beginning in September 2024, she debuted as a judge on the eighteenth edition of X Factor. Iezzi released the single "Club Astronave" on 10 December 2024. The following spring she collaborated with Fabio Rovazzi and Dani Faiv on the song "Red Flag", which was released on 9 May 2025. Later in 2025, she returned as a judge for the nineteenth edition of X Factor. Iezzi was the winning mentor of the season when her contestant Rob (Roberta Scandurra) won the season. On 7 November 2025, her single "Superstar" was released.