Don Enrique Pérez de Guzmán y Fonseca, 2nd Duke of Medina Sidonia, became the second Duke in 1468. He was also 4th Count of Niebla and 7th Lord of Sanlúcar.
- Position held
- Duke of Medina Sidonia, marquess of Gibraltar, count of Niebla, Lord of Sanlúcar
- Born
- 1430
- Died
- 1492