Emmanuelle is a feminine given name of French origin. Notable people with the given name include:
Emmanuelle Antille (born 1972), Swiss video artist
Emmanuelle Arsan (1932–2005), Thai-French novelist
Emmanuelle Atienza (2006–2025), Filipino-Taiwanese social media influencer
Emmanuelle Béart (born 1963), French actress
Emanuella Carlbeck (1829–1901), Swedish social reformer
Emmanuelle Charpentier (born 1968), French researcher in microbiology, genetics and biochemistry
Emmanuelle Chriqui (born 1975), Canadian actress
Emmanuelle Cinquin (1908–2008), Belgian and French religious sister
Emmanuelle Claret (1968–2013), French biathlete
Emmanuelle de Dampierre (1913–2012), member of the Spanish royal family
Emanuelle Felberk (born 2007), Brazilian rhythmic gymnast
Emmanuelle Gagliardi (born 1976), Swiss tennis player
Emmanuelle Grey Rossum (born 1986), known as Emmy Rossum, American actress
Emmanuelle Khanh (1937–2017), French fashion designer and stylist
Emmanuelle Lambert (born 1975), French writer
Emmanuelle Proulx, vocalist and guitarist of the Canadian indie pop band Men I Trust
Emmanuelle Seigner (born 1966), French actress, former fashion model and lead singer of Ultra Orange & Emmanuelle
Emmanuelle Vaugier (born 1976), Canadian film and television actress