21st century
He broadcast over a decade's worth of Ibiza live mixes from Space, specifically from 2001 to 2016.
In 2001, Cox began a yearly residency at Space Ibiza, a nightclub in Ibiza, Spain. He began playing on the terrace for Space's "We Love... Space on the Terrace". Following that, he played on Thursdays inside the club. For fifteen years, Cox built his residency entitled "Music is Revolution". The final season of Cox's residency was entitled "The Final Chapter" and took place every Tuesday during the summer of 2016. Cox finished the residency on 20 September 2016 by playing a vinyl and CDJ, ten-hour set. Artists who joined Cox on his final night included tINI, Popof, Nic Fanciulli and DJ Sneak. Cox also played at the closing night of the club itself on 2 October 2016.
In 2004, Cox debuted the Carl Cox & Friends arena at Ultra Music Festival, which has since taken place for twelve years. In the film Can U Feel It?, a documentary about Ultra Music Festival, Cox explains that the concept of Carl Cox & Friends came about as a result of not only wanting to play longer sets at festivals, but also to give festival goers an experience within the festival, as Carl has far more creative control over his own stage. The stage is popular with festival goers, and has featured artists like Laurent Garnier, Nic Fanciulli, Loco Dice, Marco Carola, Maceo Plex and many more. Since he created the Carl Cox & Friends concept in 2004, this curated stage has taken place at other festivals and events including Awakenings, EDC Las Vegas, The BPM Festival, Ultra Europe, Tomorrowland, Amsterdam Dance Event and many others.
Cox has performed at clubs such as the Eclipse, Shelley's Laserdome, Sterns Nightclub, Heaven, Sir Henry's, Angels and The Haçienda, as well as raves for Fantazia, Dreamscape, NASA and Amnesia House.
After his residency at Space Ibiza, in 2017 Cox played three showcases at The BPM Festival, his stage at Ultra Music Festival, and at the Social Festival in Mexico and Colombia. Also in 2017, Cox was named the global ambassador of Ultra Music Festival's techno and house music concept, Resistance. He curated Pure Festival in Sydney and Melbourne, Australia, in April 2017.
After sixteen years of Cox's Global radio podcast, he announced via Facebook that he would no longer be working on the show and that it would end in February 2017.
In 2019, Cox travelled to Australia and worked with Gavin Campbell, producing a remix of Yothu Yindi's song "Treaty", performing live outdoors with Yothu Yindi & The Treaty Project at the Babylon Festival, Carapooee, Victoria, in February 2019.
For 2020, he announced via the Goodwood website that he would be playing a summer festival DJ set at the first of the Three Friday nights at Goodwood Racecourse with a special dedication to the Lloyds before their departure.