Television and film
Her first role came in 2006 on the television show Agatha Christie's Poirot as 'Miss Sorrel'. The same year, Scholey played Diana Rivers in BBC television adaptation of Jane Eyre. She also appeared in Holby City and Doctors.
In 2009, she played the lead role of Michelle "Midge" Lerner in the BBC Three comedy drama Personal Affairs, alongside Laura Aikman, Ruth Negga, and Maimie McCoy. She played Lauren Drake in the BBC supernatural drama Being Human (2009) and Contessina de Medici in the television series, Medici: Masters of Florence (2016).
She made her feature film debut in 2014, when she performed the leading role of Maddie in the jukebox musical feature film Walking on Sunshine.
In 2018, she began starring in the legal drama series The Split as Nina Defoe. She co-starred in the cast with Stephen Mangan, Fiona Button, and Barry Atsma until the series finale in 2022.
In 2020, Scholey returned to the BBC screens with The Salisbury Poisoning, a series based on the real-life Novichok poisonings of Sergei Skripal and his daughter.
In 2021, she played the major recurring role of Claire Brown in Doctor Who: Flux.
In 2023, she appeared in Janis Pugh's musical film Chuck Chuck Baby. She starred alongside Louise Brealey and Sorcha Cusack. That July, she played Anne-Marie Blake in the true crime drama miniseries The Sixth Commandment. In December, Scholey starred in the miniseries adaptation of Alice Hunter's novel of the same name, The Serial Killer's Wife. She portrayed the titular wife of Tom (Jack Farthing).
Scholey portrayed journalist Beattie Johnson in the 2024 television adaptation of Jilly Cooper's Rivals. The same year, she led the Dead and Buried drama mini series, portraying a woman meeting her brother's murderer again. In November, she joined the season 2 cast of the British psychological thriller series The Couple Next Door.
