Plot
Two American graduate students from New York City, David Kessler and Jack Goodman, are trekking across the North York Moors. As night falls, they stop at the Slaughtered Lamb, a local pub. Jack notices a five-pointed star on the pub's wall. When he asks about it, the pub-goers grow hostile, prompting him and David to leave. The pub-goers warn the pair to keep to the road, stay clear of the moors and beware of the full moon. David and Jack wander off the road and onto the moors, where a vicious creature attacks them. Jack is mauled to death and David is severely injured. The beast is shot and killed by some concerned pub-goers who followed the pair. Instead of an animal carcass, David sees a naked dead man lying next to him before passing out.
David wakes up three weeks later in a London hospital. Inspector Villiers interviews David and informs him that the locals reported that an escaped lunatic attacked him and Jack. David insists a rabid dog or wolf attacked them. An undead Jack later appears to David and explains that they were attacked by a werewolf; since David was bitten, he is now a werewolf too. Jack is cursed to walk the earth in limbo, neither dead nor alive, until the wolf's bloodline is severed. Jack urges David to kill himself before the next full moon so he does not harm anyone.
Dr. J. S. Hirsch visits the Slaughtered Lamb to investigate, suspecting that David might have been influenced by local superstitions. When asked about the incident, the pub-goers deny any knowledge of David, Jack or the attack. However, one distraught pub-goer privately tells Dr. Hirsch that David will endanger other people when he transforms.
Upon being released from the hospital, David stays with Alex Price, the nurse who cared for him. Alex tells David that she is concerned about his mental health, as he has been having hyper realistic dreams and nightmares. Jack, now even more decayed, appears and warns David that he will become a werewolf the following night and again advises him to commit suicide. David refuses to believe him but when the full moon rises, he painfully transforms into a werewolf inside Alex's flat. He prowls the streets and the London Underground, killing six people. He wakes up the next morning naked on the floor of a wolf enclosure at the London Zoo with no recollection of what happened and returns to Alex's flat.
After learning of the previous night's murders and realizing that he is responsible, David unsuccessfully attempts to get himself arrested in Trafalgar Square. He calls his family to say he loves them, then loses the courage to slit his wrists with a pocket knife. David spots Jack, whose skeleton is now showing, outside an adult cinema. Inside, Jack introduces David to his previous night's victims, some of whom are furious with David and suggest different suicide methods to free them from their undead state.
David transforms into a werewolf while still in the theatre. He decapitates Inspector Villiers and wreaks havoc in the streets, killing several motorists and bystanders. The police surround and trap David in an alleyway. Alex arrives, runs down the alley, and tries calming David by professing her love to him. Although David's consciousness briefly emerges to recognize Alex, the beast takes over and lunges towards her, forcing the police to shoot him dead. David's body reverts to human form in front of Alex as she mourns him.
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